"According to Kozikowski, he and others in the field of CNS drug discovery “may think we know what we are doing. We may think we are clever enough to invent a magic bullet for a brain disease by making a small molecule that interacts with a specific receptor, transporter, or enzyme. But we may in fact be fooling ourselves. There’s a level of impossibility in the idea that a single small molecule can fix a complex organ like the brain.” Some psychiatric diagnoses, Kozikowski believes, have “rocky” foundations. “Some conditions are just part of life” and don’t require pharmaceutical intervention"
C&EN Talks With Alan Kozikowski | July 30, 2012 Issue - Vol. 90 Issue 31 | Chemical & Engineering News
This thought has always been in the back of my mind (IRONICALLY?)